Nanodisc Human TRPC6-Strep Protein (HDFP1382)
- SKU:
- HDFP1382
- Size:
- 10μg
- Target:
- TRPC6
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
Product Name: | Nanodisc Human TRPC6-Strep Protein |
SKU: | HDFP1382 |
Size: | 10μg |
Target: | TRPC6 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | FSGS2, TRP6 |
Protein Families: | Ion Channels: Transient receptor potential. |
Protein Description: | Human TRPC6-Strep full length protein-synthetic nanodisc |
Molecular Weight: | The human full length TRPC6-Strep protein has a MW of 106.3 kDa |
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009]
Uniprot ID: | Q9Y210 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |