Human STXBP6 Recombinant Protein (RPPB4871)
- SKU:
- RPPB4871
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8NFX7
Description
| Product Name: | Human STXBP6 Recombinant Protein |
| Product Code: | RPPB4871 |
| Size: | 20µg |
| Species: | Human |
| Target: | STXBP6 |
| Synonyms: | Syntaxin-binding protein 6, Amisyn, STXBP6, HSPC156, Syntaxin Binding Protein 6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | STXBP6 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol, 0.15M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSAKSAI SKEIFAPLDE RMLGAVQVKR RTKKKIPFLA TGGQGEYLTY ICLSVTNKKP TQASITKVKQ FEGSTSFVRR SQWMLEQLRQ VNGIDPNGDS AEFDLLFENA FDQWVASTAS EKCTFFQILH HTCQRYLTDR KPEFINCQSK IMGGNSILHS AADSVTSAVQ KASQALNERG ERLGRAEEKT EDLKNSAQQF AETAHKLAMK HKC |
Syntaxin-binding protein 6 (STXBP6) binds components of the SNARE complex and takes part in regulating SNARE complex configuration. STXBP6 forms non-fusogenic complexes with SNAP25 and STX1A and modulates the formation of SNARE complexes and exocytosis.
STXBP6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 233 amino acids (1-210 a.a.) and having a molecular mass of 25.9kDa.STXBP6 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | STXBP6: Forms non-fusogenic complexes with SNAP25 and STX1A and may thereby modulate the formation of functional SNARE complexes and exocytosis. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q12 Cellular Component: exocyst; plasma membrane Molecular Function:GTP-Rho binding; phosphatidylinositol-4,5-bisphosphate binding Biological Process: exocyst localization; Golgi to plasma membrane transport; negative regulation of exocytosis |
| NCBI Summary: | STXBP6 binds components of the SNARE complex (see MIM 603215) and may be involved in regulating SNARE complex formation (Scales et al., 2002 [PubMed 12145319]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8NFX7 |
| NCBI GenInfo Identifier: | 34222907 |
| NCBI Gene ID: | 29091 |
| NCBI Accession: | Q8NFX7.2 |
| UniProt Secondary Accession: | Q8NFX7,Q8N3H1, Q8N8D5, Q96GF3, Q9P008, D3DS78, |
| UniProt Related Accession: | Q8NFX7 |
| Molecular Weight: | 11,587 Da |
| NCBI Full Name: | Syntaxin-binding protein 6 |
| NCBI Synonym Full Names: | syntaxin binding protein 6 |
| NCBI Official Symbol: | STXBP6�� |
| NCBI Official Synonym Symbols: | amisyn; HSPC156�� |
| NCBI Protein Information: | syntaxin-binding protein 6 |
| UniProt Protein Name: | Syntaxin-binding protein 6 |
| UniProt Synonym Protein Names: | Amisyn |
| Protein Family: | Syntaxin-binding protein |
| UniProt Gene Name: | STXBP6�� |
| UniProt Entry Name: | STXB6_HUMAN |
