Human SH3GL3 Recombinant Protein (RPPB4667)
- SKU:
- RPPB4667
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q99963
Description
| Product Name: | Human SH3GL3 Recombinant Protein |
| Product Code: | RPPB4667 |
| Size: | 20µg |
| Species: | Human |
| Target: | SH3GL3 |
| Synonyms: | SH3-Domain GRB2-Like 3, SH3 Domain-Containing GRB2-Like Protein 3, SH3 Domain Protein 2C, Endophilin-3, EEN-B2, SH3D2C, CNSA3, Endophilin-A3, HsT19371, SH3P13, EEN-2B-L3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | SH3GL3 protein solution (1mg/ml) containing PBS (pH 7.4), 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSVAGLK KQFHKASQLF SEKISGAEGT KLDDEFLDME RKIDVTNKVV AEILSKTTEY LQPNPAYRAK LGMLNTVSKI RGQVKTTGYP QTEGLLGDCM LKYGKELGED STFGNALIEV GESMKLMAEV KDSLDINVKQ TFIDPLQLLQ DKDLKEIGHH LKKLEGRRLD YDYKKKRVGK IPDEEVRQAV EKFEESKELA ERSMFNFLEN DVEQVSQLAV FIEAALDYHR QSTEILQELQ SKLQMRISAA SSVPRREYKP RPVKRSSSEL NGVSTTSVVK TTGSNIPMDQ PCCRGLYDFE PENQGELGFK EGDIITLTNQ IDENWYEGMI HGESGFFPIN YVEVIVPLPQ |
SH3-DomainGRB2-Like 3, also known as SH3GL3, is a part of the endophilin family. SH3GL3 contains1 BAR domain and 1 SH3 domain and takes part in endocytosis. SH3GL3 is aprotein coding gene which drafts proteins with high curvature tomembranes.
SH3GL3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 370 amino acids (1-347 a.a) and having a molecular mass of 41.7kDa. SH3GL3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | SH3GL3: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. Belongs to the endophilin family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 15q24 Cellular Component: early endosome membrane Molecular Function:identical protein binding; protein binding; lipid binding Biological Process: central nervous system development; endocytosis; signal transduction |
| UniProt Code: | Q99963 |
| NCBI GenInfo Identifier: | 12643798 |
| NCBI Gene ID: | 6457 |
| NCBI Accession: | Q99963.1 |
| UniProt Related Accession: | Q99963 |
| Molecular Weight: | |
| NCBI Full Name: | Endophilin-A3 |
| NCBI Synonym Full Names: | SH3 domain containing GRB2 like 3, endophilin A3 |
| NCBI Official Symbol: | SH3GL3�� |
| NCBI Official Synonym Symbols: | CNSA3; EEN-B2; SH3D2C; SH3P13; HsT19371�� |
| NCBI Protein Information: | endophilin-A3 |
| UniProt Protein Name: | Endophilin-A3 |
| UniProt Synonym Protein Names: | EEN-B2; Endophilin-3; SH3 domain protein 2C; SH3 domain-containing GRB2-like protein 3 |
| UniProt Gene Name: | SH3GL3�� |
| UniProt Entry Name: | SH3G3_HUMAN |
