Human PPIL3 Recombinant Protein (RPPB1548)
- SKU:
- RPPB1548
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H2H8
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human PPIL3 Recombinant Protein |
| Product Code: | RPPB1548 |
| Size: | 20µg |
| Species: | Human |
| Target: | PPIL3 |
| Synonyms: | Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Cyclophilin J, CyPJ, Cyclophilin-like protein PPIL3, Rotamase PPIL3, PPIL3. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PPIL3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSVTLHTDVG DIKIEVFCER TPKTCENFLA LCASNYYNGC IFHRNIKGFM VQTGDPTGTG RGGNSIWGKK FEDEYSEYLK HNVRGVVSMA NNGPNTNGSQ FFITYGKQPH LDMKYTVFGK VIDGLETLDE LEKLPVNEKT YRPLNDVHIK DITIHANPFA Q |
| Biological Activity: | Specific activity is > 280 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin. |
Peptidyl-prolyl cis-trans isomerase-like 3 (PPIL3) belongs to the cyclophilin family which catalyzes the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. PPIL3 acts either as catalyst or as molecular chaperone in protein-folding events.
PPIL3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 181 amino acids (1-161 a.a.) and having a molecular mass of 20.3kDa.PPIL3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PPIL3: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing. Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 5.2.1.8; Spliceosome; Isomerase; CyclophilinChromosomal Location of Human Ortholog: 2q33.1Molecular Function: peptidyl-prolyl cis-trans isomerase activity; protein bindingBiological Process: nuclear mRNA splicing, via spliceosome |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2008] |
| UniProt Code: | Q9H2H8 |
| NCBI GenInfo Identifier: | 73921766 |
| NCBI Gene ID: | 53938 |
| NCBI Accession: | Q9H2H8.1 |
| UniProt Secondary Accession: | Q9H2H8,Q86WF9, Q96IA9, Q9BXZ1 |
| UniProt Related Accession: | Q9H2H8 |
| Molecular Weight: | 18,627 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase-like 3 |
| NCBI Synonym Full Names: | peptidylprolyl isomerase like 3 |
| NCBI Official Symbol: | PPIL3�� |
| NCBI Official Synonym Symbols: | CYPJ�� |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase-like 3 |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase-like 3 |
| UniProt Synonym Protein Names: | Cyclophilin J; CyPJ; Cyclophilin-like protein PPIL3; Rotamase PPIL3 |
| Protein Family: | Peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | PPIL3�� |
| UniProt Entry Name: | PPIL3_HUMAN |
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