Nanodisc Human P2RY1-Strep Protein (HDFP1153)
- SKU:
- HDFP1153
- Size:
- 10μg
- Target:
- P2RY1
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
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Description
| Product Name: | Nanodisc Human P2RY1-Strep Protein |
| SKU: | HDFP1153 |
| Size: | 10μg |
| Target: | P2RY1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | P2Y1, SARCC |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human P2RY1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class A Rhodopsin-like, Nucleotide GPCRs. |
| Molecular Weight: | The human full length P2RY1-Strep protein has a MW of 42.1 kDa |
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008]
| Uniprot ID: | P47900 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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