Human MTHSFD Recombinant Protein (RPPB4018)
- SKU:
- RPPB4018
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q2M296
Frequently bought together:
Description
| Product Name: | Human MTHSFD Recombinant Protein |
| Product Code: | RPPB4018 |
| Size: | 20µg |
| Species: | Human |
| Target: | MTHSFD |
| Synonyms: | Methenyltetrahydrofolate synthase domain-containing protein, Methenyltetrahydrofolate synthase domaincontaining protein, Methenyltetrahydrofolate synthase |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The MTHSFD solution (0.25mg/ml) contains 30% glycerol, 1mM DTT and Phosphate-Buffered Saline (pH 7.4). |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMEPRAVG VSKQDIREQI WGYMESQNLA DFPRPVHHRI PNFKGASHAA EQLPRLQAFK TARTIKVNPD APQKSARFFV LESKKTLLVP TPRLRTGLFN KITPPPGATK DILRKCATSQ GVRNYSVPIG LDSRVLVDLV VVGSVAVSEK GWRIGKGEGY ADLEYAMMVS MGAVSKETPV VTIVHDCQVV DIPEELVEEH DITVDYILTP TRVIATGCKR PKPMGITWFK ISLEMMEKIP ILRSLRAREQ QAGKDVTLQG EHQHLPEPGC QQTVPLSVGR RPPDTPGPET NSMEAAPGSP PGEGAPLAAD VYVGNLPGDA RVSDLKRALR ELGSVPLRLT WQGPRRRAFL HYPDSAAAQQ AVSCLQGLRL GTDTLRVALA�RQQRDK |
MTHSFD, also known as Methenyltetrahydrofolate Synthetase Domain Containing protein, is linked to Pancreas, Annular and Gastrointestinal Defects. It has also been associated with Immunodeficiency Syndrome. Some of the Gene Ontology annotations that are related to the MTHSFD gene are nucleic acid binding and nucleotide binding.
MTHSFD Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 406 amino acids (1-383 a.a.) and having a molecular mass of 44.5kDa. MTHSFD is fused to a 23 amino acid His tag at N-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MTHFSD: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 16q24.1 |
| UniProt Code: | Q2M296 |
| NCBI GenInfo Identifier: | 209572652 |
| NCBI Gene ID: | 64779 |
| NCBI Accession: | Q2M296.2 |
| UniProt Secondary Accession: | Q2M296,Q9H878, Q9H954, A8MQ77, B7ZLC0, B7ZLC2, D3DUM9 E9PAM1, |
| UniProt Related Accession: | Q2M296 |
| Molecular Weight: | 41,996 Da |
| NCBI Full Name: | Methenyltetrahydrofolate synthase domain-containing protein |
| NCBI Synonym Full Names: | methenyltetrahydrofolate synthetase domain containing |
| NCBI Official Symbol: | MTHFSD�� |
| NCBI Protein Information: | methenyltetrahydrofolate synthase domain-containing protein |
| UniProt Protein Name: | Methenyltetrahydrofolate synthase domain-containing protein |
| Protein Family: | Methenyltetrahydrofolate synthase domain-containing protein |
| UniProt Gene Name: | MTHFSD�� |
| UniProt Entry Name: | MTHSD_HUMAN |
