Human MRPS2 Recombinant Protein (RPPB4006)
- SKU:
- RPPB4006
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9Y399
Description
| Product Name: | Human MRPS2 Recombinant Protein |
| Product Code: | RPPB4006 |
| Size: | 20µg |
| Species: | Human |
| Target: | MRPS2 |
| Synonyms: | Mitochondrial ribosomal protein S2, CGI-91, MRP-S2, S2mt, 28S ribosomal protein S2, mitochondrial, MRPS2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The MRPS2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMATSSAA LPRILGAGAR APSRWLGFLG KATPRPARPS RRTLGSATAL MIRESEDSTD FNDKILNEPL KHSDFFNVKE LFSVRSLFDA RVHLGHKAGC RHRFMEPYIF GSRLDHDIID LEQTATHLQL ALNFTAHMAY RKGIILFISR NRQFSYLIEN MARDCGEYAH TRYFRGGMLT NARLLFGPTV RLPDLIIFLH TLNNIFEPHV AVRDAAKMNI PTVGIVDTNC NPCLITYPVP GNDDSPLAVH LYCRLFQTAI TRAKEKRQQV EALYRLQGQK EPGDQGPAHP PGADMSHSL |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit and have about 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Mitochondrial Ribosomal Protein S2 (MRPS2) is a 28S subunit protein which is a part of the ribosomal protein S2 family and comprises a 12S rRNA and about 30 distinct proteins.
MRPS2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 319 amino acids (1-296) and having a molecular mass of 35.6 kDa.MRPS2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | MRPS2: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
| UniProt Protein Details: | Protein type:Mitochondrial; Ribosomal; Translation Chromosomal Location of Human Ortholog: 9q34 Cellular Component: mitochondrial small ribosomal subunit; mitochondrion Molecular Function:structural constituent of ribosome Biological Process: mitochondrial translation; positive regulation of defense response to virus by host; translation |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012] |
| UniProt Code: | Q9Y399 |
| NCBI GenInfo Identifier: | 24212389 |
| NCBI Gene ID: | 51116 |
| NCBI Accession: | Q9Y399.1 |
| UniProt Secondary Accession: | Q9Y399,Q5T899, Q9BSQ4, |
| UniProt Related Accession: | Q9Y399 |
| Molecular Weight: | 33,249 Da |
| NCBI Full Name: | 28S ribosomal protein S2, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein S2 |
| NCBI Official Symbol: | MRPS2�� |
| NCBI Official Synonym Symbols: | S2mt; CGI-91; MRP-S2�� |
| NCBI Protein Information: | 28S ribosomal protein S2, mitochondrial |
| UniProt Protein Name: | 28S ribosomal protein S2, mitochondrial |
| Protein Family: | 28S ribosomal protein |
| UniProt Gene Name: | MRPS2�� |
| UniProt Entry Name: | RT02_HUMAN |
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