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Nanodisc Human LT4R1-Strep Protein (HDFP1065)

SKU:
HDFP1065
Size:
10μg
Target:
LT4R1
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
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Description

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Product Name:Nanodisc Human LT4R1-Strep Protein
SKU:HDFP1065
Size:10μg
Target:LT4R1
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:BLT1, BLTR, CMKRL1, GPR16, LTB4R1, LTBR1, P2RY7, P2Y7
Protein Families:GPCR, Transmembrane, Druggable Genome.
Protein Description:Human LT4R1-Strep full length protein-synthetic nanodisc
Protein Pathways:GPCRDB Class A Rhodopsin-like, Nucleotide GPCRs, Cancer, Chemokines, Asthma, Autoimmune & Inflammatory Response, Chemokine and Receptor.
Molecular Weight:The human full length LT4R1-Strep protein has a MW of 37.6 kDa

Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.[UniProtKB/Swiss-Prot Function]

Uniprot ID:Q15722
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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