Nanodisc Human LPAR2-Strep Protein (HDFP1059)
- SKU:
- HDFP1059
- Size:
- 10μg
- Target:
- LPAR2
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human LPAR2-Strep Protein |
| SKU: | HDFP1059 |
| Size: | 10μg |
| Target: | LPAR2 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | EDG-4, EDG4, LPA-2, LPA2 |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human LPAR2-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Cancer, G-Protein Coupled Receptors Signaling Pathway. |
| Molecular Weight: | The human full length LPAR2-Strep protein has a MW of 38.7 kDa |
This gene encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2 mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
| Uniprot ID: | Q9HBW0 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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