Nanodisc Human LGR5-Strep Protein (HDFP813)
- SKU:
- HDFP813
- Size:
- 10μg
- Target:
- LGR5
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human LGR5-Strep Protein |
| SKU: | HDFP813 |
| Size: | 10μg |
| Target: | LGR5 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | FEX; GPR49; GPR67; GRP49; HG38 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human LGR5-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length LGR5-Strep protein has a MW of 100 kDa |
The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
| Uniprot ID: | O75473 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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