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GenieFluor 488 Anti-Human HLA-A,B,C Antibody [W6/32] (AGEL1622)

SKU:
AGEL1622
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a,k
Clone:
W6/32
Conjugation:
AF 488
$263 - $899
Frequently bought together:

Description

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GenieFluor 488 Anti-Human HLA-A,B,C Antibody [W6/32]

The Human HLA-A-B-C Monoclonal Antibody (AF488 Conjugated) W6/32 (AGEL1622) is a specialized antibody designed for research involving human HLA (Human Leukocyte Antigen) class I molecules. These molecules play a crucial role in the regulation of the immune system by presenting antigens to T cells, which triggers the immune response.This monoclonal antibody, conjugated with AF488 for fluorescence detection, specifically targets the HLA-A, HLA-B, and HLA-C class I molecules. It is highly reactive with human samples, making it a valuable tool for immunology research, transplantation studies, and investigations into autoimmune diseases. The W6/32 clone of this antibody is well-characterized and widely used in the scientific community.By binding to the HLA class I molecules, the AF488-conjugated W6/32 antibody enables the precise detection and analysis of these critical components of the immune system.

It allows researchers to visualize and study the expression and function of HLA-A, HLA-B, and HLA-C in various cell types and tissues, providing valuable insights into immune responses and diseases related to immune dysregulation.This monoclonal antibody is an essential tool for studies aiming to understand the complex mechanisms of immune recognition and response, as well as for identifying potential therapeutic targets for conditions such as autoimmune diseases, infections, and cancer. Its specificity and high performance make it a valuable asset for any research aiming to unravel the intricacies of the human immune system and its role in health and disease.

Product Title:GenieFluor 488 Anti-Human HLA-A,B,C Antibody [W6/32]
SKU:AGEL1622
Size:20 Tests, 100 Tests, 200 Tests
Clone No:W6/32
Synonyms:Major Histocompatibility Class I; MHC class I;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:Genie Fluor 488 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04439 P01889 P10321
Gene ID:3105
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.

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