Human FAM84A Recombinant Protein (RPPB3514)
- SKU:
- RPPB3514
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96KN4
Description
| Product Name: | Human FAM84A Recombinant Protein |
| Product Code: | RPPB3514 |
| Size: | 20µg |
| Species: | Human |
| Target: | FAM84A |
| Synonyms: | Family with Sequence Similarity 84 Member A, Neurological/Sensory 1, Neurologic Sensory Protein 1, NSE1, PP11517, Protein FAM84A. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The FAM84A solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGNQLDR ITHLNYSELP TGDPSGIEKD ELRVGVAYFF SDDEEDLDER GQPDKFGVKA PPGCTPCPES PSRHHHHLLH QLVLNETQFS AFRGQECIFS KVSGGPQGAD LSVYAVTALP ALCEPGDLLE LLWLQPAPEP PAPAPHWAVY VGGGQIIHLH QGEIRQDSLY EAGAANVGRV VNSWYRYRPL VAELVVQNAC GHLGLKSEEI CWTNSESFAA WCRFGKREFK AGGEVPAGTQ PPQQQYYLKV HLGENKVHTA RFHSLEDLIR EKRRIDASGR LRVLQELADL VDDKE |
FAM84A is a member of the FAM84 family of proteins and is primarily expressed in testis. FAM84A is restricted to a subcellular membrane region in which there is no interaction between adjoining cells and takes part in cell morphology. Additionally, FAM84A expression increases cell motility which can result in invasion and metastasis of cancer cells. FAM84A is up-regulated in pancreatic cancer, colorectal cancer lung cancer, bladder cancer tissues and cholangiocarcinoma.
FAM84A Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 315 amino acids (1-292) and having a molecular mass of 34.9kDa.FAM84A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | FAM84A: Belongs to the FAM84 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 2p24.3 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96KN4 |
| NCBI GenInfo Identifier: | 281371408 |
| NCBI Gene ID: | 151354 |
| NCBI Accession: | NP_660158.2 |
| UniProt Secondary Accession: | Q96KN4,Q86UZ2, Q8NAH7, Q8TAM5, A6NP76 |
| UniProt Related Accession: | Q96KN4 |
| Molecular Weight: | 37,751 Da |
| NCBI Full Name: | protein FAM84A |
| NCBI Synonym Full Names: | family with sequence similarity 84, member A |
| NCBI Official Symbol: | FAM84A�� |
| NCBI Official Synonym Symbols: | NSE1; PP11517�� |
| NCBI Protein Information: | protein FAM84A; neurologic sensory protein 1; neurological/sensory 1 |
| UniProt Protein Name: | Protein FAM84A |
| UniProt Synonym Protein Names: | Neurologic sensory protein 1; NSE1 |
| Protein Family: | Tubulin polymerization-promoting protein family |
| UniProt Gene Name: | FAM84A�� |
| UniProt Entry Name: | FA84A_HUMAN |
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