Human DCTN6 Recombinant Protein (RPPB3339)
- SKU:
- RPPB3339
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O00399
Description
| Product Name: | Human DCTN6 Recombinant Protein |
| Product Code: | RPPB3339 |
| Size: | 20µg |
| Species: | Human |
| Target: | DCTN6 |
| Synonyms: | Dynactin 6, WS3, Dynactin Subunit P27, Protein WS-3, P27,Novel RGD-Containing Protein, Dynactin Subunit 6, WS-3, Dynactin subunit 6. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | DCTN6 protein solution (1mg/ml) containing PhosphateBuffered Saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAEKTQK SVKIAPGAVV CVESEIRGDV TIGPRTVIHP KARIIAEAGPIVIGEGNLIE EQALIINAYP DNITPDTEDP EPKPMIIGTN NVFEVGCYSQ AMKMGDNNVI ESKAYVGRNVILTSGCIIGA CCNLNTFEVI PENTVIYGAD CLRRVQTERPQPQTLQLDFL MKILPNYHHL KKTMKGSSTP VKN |
Dynactin 6, also known as DCTN6 is a member of the dynactin subunits 5/6family. DCTN6 includes an RGD (Arg-Gly-Asp) motif in the N-terminal region,which confers adhesive properties to macromolecular proteins such asfibronectin. DCTN6 has a high degree of sequence resemblance with the mousehomolog, which has been found to participate in mitochondrial biogenesis.Moreover, the precise biological function of DCTN6 is unknown.
DCTN6 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 213 amino acids (1-190 a.a) andhaving a molecular mass of 23.1kDa.DCTN6 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | dynactin 6: contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 8p12 Cellular Component: centrosome; cytosol Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport |
| NCBI Summary: | The protein encoded by this gene contains an RGD (Arg-Gly-Asp) motif in the N-terminal region, which confers adhesive properties to macromolecular proteins like fibronectin. It shares a high degree of sequence similarity with the mouse homolog, which has been suggested to play a role in mitochondrial biogenesis. The exact biological function of this gene is not known. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00399 |
| NCBI GenInfo Identifier: | 3024856 |
| NCBI Gene ID: | 10671 |
| NCBI Accession: | O00399.1 |
| UniProt Secondary Accession: | O00399,B2RAC1, |
| UniProt Related Accession: | O00399 |
| Molecular Weight: | 20,747 Da |
| NCBI Full Name: | Dynactin subunit 6 |
| NCBI Synonym Full Names: | dynactin subunit 6 |
| NCBI Official Symbol: | DCTN6�� |
| NCBI Official Synonym Symbols: | WS3; p27; WS-3�� |
| NCBI Protein Information: | dynactin subunit 6 |
| UniProt Protein Name: | Dynactin subunit 6 |
| UniProt Synonym Protein Names: | Dynactin subunit p27; Protein WS-3 |
| UniProt Gene Name: | DCTN6�� |
| UniProt Entry Name: | DCTN6_HUMAN |
