Nanodisc Human CRHR1 Protein (HDFP219)
- SKU:
- HDFP219
- Size:
- 10μg
- Target:
- CRHR1
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human CRHR1 Protein |
| SKU: | HDFP219 |
| Size: | 10μg |
| Target: | CRHR1 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human CRHR1 full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class B Secretin-like, Smooth muscle contraction, Cancer, Neurotrophin & Receptors. |
| Molecular Weight: | The human full length CRHR1 protein has a MW of 36.6kDa |
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants. Naturally-occurring readthrough transcription between this gene and upstream GeneID:147081 results in transcripts that encode isoforms that share similarity with the products of this gene. [provided by RefSeq, Aug 2016]
| Uniprot ID: | B3TIK8 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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