HSP27/HSPB1 Rabbit Monoclonal Antibody (CAB11156)
- SKU:
- CAB11156
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | HSP27/HSPB1 Rabbit Monoclonal Antibody |
SKU: | CAB11156 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-205 of human HSP27/HSPB1 (P04792). |
Sequence: | DVNH FAPD ELTV KTKD GVVE ITGK HEER QDEH GYIS RCFT RKYT LPPG VDPT QVSS SLSP EGTL TVEA PMPK LATQ SNEI TIPV TFES RAQL GGPE AAKS DETA AK |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CMT2F; HMN2B; HSP27; HSP28; Hsp25; SRP27; HS.76067; HEL-S-102; HSP27/HSPB1 |
Positive Sample: | HeLa,BxPC-3,Mouse liver,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, Cytoskeleton, Spindle. |
Calculated MW: | 23kDa |
Observed MW: | 27kDa |
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Purification Method: | Affinity purification |
Gene ID: | 3315 |
Clone Number: | ARC0531 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |