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HK3 Monoclonal Antibody [P4F5AT] (CPAB0135)

SKU:
CPAB0135
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P4F5AT
Applications:
WB
ELISA
€149
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Description

system_update_alt Datasheet

HK3 Monoclonal Antibody [P4F5AT] (CPAB0135)

The HK3 Polyclonal Antibody (CPAB0135) is a key tool for researchers studying the HK3 protein, a crucial enzyme in the glycolysis pathway. This antibody, produced in rabbits, has high specificity and sensitivity for detecting HK3 in human samples, making it suitable for use in a variety of applications including Western blotting and immunohistochemistry.HK3 is essential for the conversion of glucose to glucose-6-phosphate, a key step in glucose metabolism that provides energy for cells. Dysregulation of HK3 has been linked to various diseases, including cancer and metabolic disorders, making it a promising target for therapeutic interventions.

By targeting the HK3 protein, researchers can gain valuable insights into the molecular mechanisms underlying metabolic disorders and potentially identify novel therapeutic strategies for treating related diseases. The HK3 Polyclonal Antibody is a valuable tool for exploring the role of HK3 in health and disease, providing researchers with a reliable means to study this important enzyme.

Product Name:HK3 Antibody
Product Sku:CPAB0135
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Hexokinase-3 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Hexokinase-3 amino acids 1-923 purified from Ecoli.
Clone:P4F5AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:Hexokinase-3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK3 encodes hexokinase 3. Similar to hexokinases 1 and 2, this allosteric enzyme is inhibited by its product glucose-6-phosphate. Hexokinase3 lacks the hydrophobic N-terminal sequence critical for targeting to mitochondria. Hexpkinase3 may have anabolic functions, providing H6P for glycogen or lipid synthesis.
Synonyms:Hexokinase-3, EC 2.7.1.1, Hexokinase type III, HK III, HXK3, HK3.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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