The Histone H1.0 Rabbit Monoclonal Antibody (CAB4342) is a specialized research tool for studying histone H1.0, a key protein involved in chromatin structure and gene regulation. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for human samples, making it ideal for use in various experimental techniques such as Western blotting.Histone H1.0 is a subtype of histone H1 that plays a crucial role in nucleosome organization and gene expression. Research suggests that histone H1.0 may be involved in the regulation of gene transcription and chromatin remodeling processes. By using the Histone H1.0 Rabbit Monoclonal Antibody (CAB4342), researchers can investigate the function and localization of histone H1.
0 in different cell types and experimental models.The study of histone proteins, including histone H1.0, is essential for understanding the epigenetic mechanisms that control gene activity and cellular functions. Dysregulation of histone H1.0 has been linked to various diseases, including cancer, developmental disorders, and neurodegenerative conditions. Therefore, the Histone H1.0 Rabbit Monoclonal Antibody (CAB4342) is a valuable tool for researchers interested in epigenetics, chromatin biology, and disease mechanisms involving histone modifications.
Product Name:
Histone H1.0 Rabbit Monoclonal Antibody
SKU:
CAB4342
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Other (Wide Range Predicted)
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Histone H1.0 (P07305).
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-independent histone that is a member of the histone H1 family.
Purification Method:
Affinity purification
Gene ID:
3005
Clone Number:
ARC1059
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Histone H1.0 Rabbit mAb (CAB4342) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
