HFE Rabbit Polyclonal Antibody (CAB1310)
- SKU:
- CAB1310
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | HFE Rabbit Polyclonal Antibody |
SKU: | CAB1310 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-306 of human HFE (NP_000401.1). |
Sequence: | SSQM WLQL SQSL KGWD HMFT VDFW TIME NHNH SKES HTLQ VILG CEMQ EDNS TEGY WKYG YDGQ DHLE FCPD TLDW RAAE PRAW PTKL EWER HKIR ARQN RAYL ERDC PAQL QQLL ELGR GVLD QQVP PLVK VTHH VTSS VTTL RCRA LNYY PQNI TMKW LKDK QPMD AKEF EPKD VLPN GDGT YQGW ITLA VPPG EEQR YTCQ VEHP GLDQ PLIV IWEP SPSG TLV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HH; HFE1; HLA-H; MVCD7; TFQTL2; HFE |
Positive Sample: | Mouse liver,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein. |
Calculated MW: | 40kDa |
Observed MW: | 50kDa |
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.
Purification Method: | Affinity purification |
Gene ID: | 3077 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |