GSK3B Monoclonal Antibody [P1F7AT] (CPAB0155)
- SKU:
- CPAB0155
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- P1F7AT
- Applications:
- WB
- ELISA
Description
GSK3B Monoclonal Antibody [P1F7AT] (CPAB0155)
The GSK3B Polyclonal Antibody (CPAB0155) is a crucial tool for research involving GSK3B, a key signaling molecule involved in various cellular processes such as growth, proliferation, and apoptosis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the GSK3B protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for studies in cell biology and cancer research.GSK3B, also known as glycogen synthase kinase 3 beta, is a critical regulator of numerous signaling pathways that influence cell growth and survival.
Dysregulation of GSK3B has been implicated in the development of various diseases, including cancer, diabetes, and neurodegenerative disorders. Understanding the functions and mechanisms of GSK3B is essential for identifying potential therapeutic targets and developing treatments for these complex conditions. This antibody provides researchers with a valuable tool to further explore the role of GSK3B in health and disease.
Product Name: | GSK3B Antibody |
Product Sku: | CPAB0155 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human GSK3B mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human GSK3B amino acids 341-42 purified from Ecoli. |
Clone: | P1F7AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | GSK3B antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | GSK3B is a serine-threonine kinase that belongs to the glycogen synthase kinase subfamily. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of the GSK3B gene may be significant to the pathogenesis of Alzheimer disease. |
Synonyms: | GSK3B, Glycogen synthase kinase-3 beta, GSK-3 beta. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |