The GPR75 Polyclonal Antibody (PACO02381) is a valuable tool for researchers studying GPR75, a G protein-coupled receptor that plays a crucial role in various cellular processes. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications. By targeting the GPR75 protein, this antibody enables researchers to detect and analyze GPR75 expression in different cell types, offering insights into its functions in processes such as metabolism, cardiovascular health, and neurological disorders.GPR75 is known for its involvement in the regulation of appetite, energy balance, and lipid metabolism, making it a potential therapeutic target for conditions like obesity, diabetes, and cardiovascular diseases.
By studying the role of GPR75 in these physiological processes, researchers can uncover new pathways for drug development and personalized medicine approaches aimed at managing metabolic disorders and improving overall health outcomes. The GPR75 Polyclonal Antibody is a valuable asset for advancing research in these areas and understanding the implications of GPR75 dysregulation in disease progression.
Antibody Name:
GPR75 Antibody
Antibody SKU:
PACO02381
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human GPR75.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
GPR75; Probable G-protein coupled receptor 75
UniProt Protein Function:
GPR75: Orphan receptor. Belongs to the G-protein coupled receptor 1 family.Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 2p16Cellular Component: integral to plasma membraneMolecular Function: C-C chemokine receptor activity; G-protein coupled receptor activityBiological Process: cell surface receptor linked signal transduction; G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]