The Gins3 Polyclonal Antibody (PACO09470) is a valuable tool for researchers studying the Gins3 protein, a key player in cellular metabolism and energy regulation. This antibody, produced using rabbits as the host, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Gins3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in biochemistry and molecular biology.
Gins3, also known as GINS complex subunit 3, is essential for DNA replication and cell proliferation, making it a critical target for research in cancer biology and genetics. Understanding the role of Gins3 in these processes is crucial for developing targeted therapies for cancer and other diseases related to dysregulated cell growth. The Gins3 Polyclonal Antibody is a valuable resource for scientists investigating the intricate mechanisms of cellular function and potential therapeutic interventions.
GINS3: The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. Belongs to the GINS3/PSF3 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 16q21Cellular Component: nucleoplasmBiological Process: DNA strand elongation during DNA replication
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein subunit of the GINS heterotetrameric complex, which is essential for the initiation of DNA replication and replisome progression in eukaryotes. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
