The GenieFluor Violet 450 Anti-Mouse CD45.2 Antibody (104-2) is a cutting-edge tool designed for researchers working with mouse models in immunology and cell biology studies. This antibody, produced by Assay Genie, is specifically engineered to target and bind to the CD45.2 protein, a crucial marker for immune cell identification and analysis.With its high specificity and sensitivity, the GenieFluor Violet 450 Anti-Mouse CD45.2 Antibody (104-2) allows for precise detection and visualization of CD45.2-expressing cells in various experimental settings. Whether used in flow cytometry, immunofluorescence, or other applications, this antibody provides reliable and reproducible results, facilitating accurate data interpretation and experimental outcomes.The CD45.2 protein, a key component of the immune system, plays an essential role in immune cell signaling and activation.
By targeting CD45.2 with the GenieFluor Violet 450 Anti-Mouse CD45.2 Antibody (104-2), researchers can gain valuable insights into immune cell populations, differentiation processes, and immune responses in mouse models. This antibody is a valuable tool for investigating immune function, inflammation, and disease mechanisms, making it a valuable addition to any research laboratory focusing on immunology, cancer biology, or related fields.Overall, the GenieFluor Violet 450 Anti-Mouse CD45.2 Antibody (104-2) from Assay Genie represents a high-quality reagent that enables precise and efficient analysis of CD45.2-expressing cells in mouse models, contributing to advancements in our understanding of immune system dynamics and immune-related diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.