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GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL2959)

SKU:
AGEL2959
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
MIAP410
Conjugation:
AFViolet 450
€289 - €649
Frequently bought together:

Description

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GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) from Assay Genie is a cutting-edge research tool designed for the detection and analysis of CD47, a cell surface protein involved in cell signaling and immune responses. This antibody, produced using advanced technology, exhibits high specificity and sensitivity in detecting CD47 in human, mouse, and rat samples, making it a versatile tool for various research applications.CD47, also known as integrin-associated protein, is a multifunctional protein that plays a crucial role in immune response modulation, cell adhesion, and cell communication. Its involvement in functions such as phagocytosis inhibition and regulation of cell survival and proliferation has made it a target of interest in studies related to immunology, cancer research, and therapeutic development.

By utilizing the GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody (MIAP410), researchers can gain valuable insights into the expression and activity of CD47 in different biological contexts. This antibody's superior performance in applications such as flow cytometry and immunofluorescence allows for precise and reliable detection of CD47 in various cell types and tissues, enabling in-depth investigations into its function and potential therapeutic implications.Overall, the GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody (MIAP410) offers researchers a powerful tool to advance their understanding of CD47 biology and its implications in health and disease, paving the way for innovative discoveries and potential therapeutic strategies.

Product Title:GenieFluor Violet 450 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL2959
Size:25µg, 100µg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie FluorViolet 450
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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