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GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL3069)

SKU:
AGEL3069
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, κ
Clone:
IM7
Conjugation:
AFRed 780
$251 - $515
Frequently bought together:

Description

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GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7]

The GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody (IM7) is a cutting-edge research tool offered by Assay Genie for the study of CD44, a cell surface glycoprotein known for its role in cell adhesion and migration. This antibody, developed for use in both human and mouse samples, is specifically designed to target the CD44 protein, allowing for precise detection and analysis in a variety of cell types.CD44 is a multifunctional molecule involved in numerous biological processes, including cell signaling, lymphocyte activation, and tumor metastasis. Its diverse functions make it a key molecule of interest in research areas such as immunology, oncology, and stem cell biology.

The GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody (IM7) provides researchers with a powerful tool to investigate the expression and localization of CD44 in different experimental settings.With its high specificity and sensitivity, this antibody is ideal for applications such as flow cytometry, immunofluorescence, and immunohistochemistry. By utilizing this advanced antibody, researchers can gain valuable insights into the role of CD44 in various physiological and pathological processes, paving the way for potential therapeutic interventions in diseases like cancer, inflammation, and immune disorders.

Product Title:GenieFluor Red 780 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL3069
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor Red 780 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie FluorRed 780
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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