The GenieFluor 488 Anti-Mouse Perforin Antibody (S16009A-AGEL3308) is a cutting-edge research tool designed for scientists studying immune responses and cell-mediated cytotoxicity. This high-quality antibody, specifically developed for use in mouse models, targets the perforin protein which plays a key role in the immune response by inducing apoptosis in target cells.Developed and validated by Assay Genie, this antibody is crucial for detecting and analyzing perforin expression in various cell types, providing valuable insights into the mechanisms of immune cell cytotoxicity. It is ideal for use in techniques such as immunofluorescence, flow cytometry, and immunohistochemistry, enabling researchers to visualize and quantify perforin levels in experimental models.
Perforin is a critical component of the immune system's defense against infected or abnormal cells, making this antibody an essential tool for studies in immunology, infectious diseases, and cancer research. By targeting perforin, researchers can gain a better understanding of immune cell function and the mechanisms underlying immune-mediated cytotoxicity, paving the way for the development of novel therapies targeting these pathways.For researchers seeking to delve deeper into the intricate workings of the immune system and investigate the role of perforin in health and disease, the GenieFluor 488 Anti-Mouse Perforin Antibody stands as a valuable tool for advancing scientific knowledge and driving groundbreaking discoveries in immunology and beyond.
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P10820
Gene ID:
18646Â
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.