The GBX2 Polyclonal Antibody (CAB14733) is a valuable tool for researchers studying the GBX2 protein, a transcription factor involved in embryo development and cell differentiation. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot assays.GBX2 plays a crucial role in early embryonic development, specifically in the formation of the midbrain and hindbrain regions. Its aberrant expression has been linked to developmental disorders and certain types of cancer, making it a key target for research in developmental biology and oncology.
By using the GBX2 Polyclonal Antibody, researchers can detect and analyze the expression of GBX2 in various cell types, providing insights into its functions and potential implications in disease states. This antibody is an essential tool for studying the regulatory mechanisms of GBX2 and its impact on cellular processes, paving the way for new therapeutic strategies in the fields of embryology and cancer research.
Product Name:
GBX2 Rabbit Polyclonal Antibody
SKU:
CAB14733
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GBX2 (NP_001476.2).
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of nervous system development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including branching involved in blood vessel morphogenesis; nervous system development; and neural crest cell migration. Predicted to be part of chromatin. Predicted to be active in nucleus.
Purification Method:
Affinity purification
Gene ID:
2637
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GBX2 antibody (CAB14733) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
