null

Frataxin Monoclonal Antibody [PAT10E11AT] (CPAB0664)

SKU:
CPAB0664
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT10E11AT
Applications:
ELISA
FC
$179
Frequently bought together:

Description

system_update_alt Datasheet

Frataxin Monoclonal Antibody [PAT10E11AT] (CPAB0664)

The Frataxin Antibody (CPAB0664) is a high-quality polyclonal antibody designed for research involving frataxin, a protein involved in the regulation of iron homeostasis and mitochondrial function. The antibody is raised in rabbits and is highly reactive with human samples, making it ideal for use in Western blot and immunohistochemistry applications.Frataxin is a critical protein in the maintenance of mitochondrial function, particularly in the biosynthesis of iron-sulfur clusters. Dysregulation of frataxin has been implicated in the development of neurodegenerative disorders such as Friedreich's ataxia.

By targeting frataxin with this antibody, researchers can gain insights into the role of this protein in disease pathogenesis and potentially identify novel therapeutic targets for the treatment of mitochondrial disorders.This antibody offers researchers a valuable tool for studying frataxin biology and its implications in various disease states. Its specificity and high reactivity with human samples make it an essential component for studies in mitochondrial biology, neurodegeneration, and potential drug discovery efforts targeting frataxin-related diseases.

Product Name:Frataxin Antibody
Product Sku:CPAB0664
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Frataxin mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Frataxin protein 42-21 amino acids purified from Ecoli.
Clone:PAT10E11AT.
Reactivity:Other bodies
Applications:ELISA, Flow Cytometry
Purification Method:Frataxin antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Frataxin is a mitochondrial iron binding protein that is part of the FRATAXIN family. Frataxin functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Frataxin plays a role in iron homeostasis. Frataxin is an anti-apoptotic protein which prevents mitochondrial damage and reactive oxygen species (ROS) production.
Synonyms:FXN, Friedreich ataxia protein, Frataxin mitochondrial, FRDA, X25, FA, CyaY, FARR, MGC57199, Frataxin.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products