The FOXF2 Polyclonal Antibody (PAC017874) is a valuable tool for researchers studying the transcription factor FOXF2, which is known to play a key role in various cellular processes, including development, cell differentiation, and tissue homeostasis. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting FOXF2 in human samples, making it an excellent choice for immunohistochemistry and immunofluorescence applications.FOXF2 is a transcription factor that is involved in the regulation of numerous genes and pathways, making it a crucial player in the control of cellular function and development.
Dysregulation of FOXF2 has been implicated in various diseases, including cancer, cardiovascular disorders, and neurological conditions, highlighting its importance as a potential therapeutic target.By using the FOXF2 Polyclonal Antibody, researchers can investigate the expression and localization of FOXF2 in different cell types and tissues, providing valuable insights into its function and potential roles in disease processes. This antibody is a valuable tool for advancing our understanding of FOXF2 biology and its implications for human health.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17874(FOXF2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human placenta tissue, human normal liver tissue, Primary antibody: PACO17874(FOXF2 Antibody) at dilution 1/666, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes.
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17874(FOXF2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.
Synonyms:
forkhead box F2
UniProt Protein Function:
FOXF2: Probable transcription activator for a number of lung- specific genes.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 6p25.3Cellular Component: transcription factor complex; nucleusMolecular Function: DNA binding; sequence-specific DNA binding; transcription factor binding; transcription factor activityBiological Process: genitalia development; extracellular matrix organization and biogenesis; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; epithelial to mesenchymal transition; positive regulation of transcription from RNA polymerase II promoter; embryonic camera-type eye morphogenesis; palate development; negative regulation of transcription, DNA-dependent; embryonic gut development; establishment of polarity of embryonic epithelium
UniProt Protein Details:
NCBI Summary:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. [provided by RefSeq, Jul 2008]
