The FOXD1 Polyclonal Antibody is a valuable tool for researchers studying the FOXD1 transcription factor, which plays a crucial role in embryonic development and kidney function. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in various applications such as Western blot and immunohistochemistry.FOXD1 is known to regulate the expression of genes involved in cell differentiation and organ development, making it an important target for studies in developmental biology and kidney disease research. By binding to FOXD1, this antibody allows for the detection and analysis of the protein in different cell types, providing valuable insights into its function and potential therapeutic applications.
Given the role of FOXD1 in embryogenesis and kidney function, research using this antibody may have implications for understanding birth defects, kidney disorders, and even certain types of cancer. The FOXD1 Polyclonal Antibody is a reliable tool for investigating the molecular mechanisms underlying these conditions and advancing our knowledge in the field of developmental biology.
Product Name:
FOXD1 Polyclonal Antibody
SKU:
CAB20240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOXD1 (NP_004463.1).
Sequence:
MTLS TEMS DASG LAEE TDID VVGE GEDE EDEE EEDD DEGG GGGP RLAV PAQR RRRR RSYA GEDE LEDL EEEE DDDD ILLA PPAG GSPA PPGP APAA GAGA
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
FKHL8; FREAC4; FREAC-4; FOXD1
Positive Sample:
BxPC-3,Mouse eye,Mouse fetal,Rat kidney,Rat brain
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
46kDa
Observed MW:
57kDa
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity.
Purification Method:
Affinity purification
Gene ID:
2297
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using FOXD1 antibody (CAB20240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
