FKBP3 Rabbit Polyclonal Antibody (CAB6907)
- SKU:
- CAB6907
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | FKBP3 Rabbit Polyclonal Antibody |
SKU: | CAB6907 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3 (NP_002004.1). |
Sequence: | MAAA VPQR AWTV EQLR SEQL PKKD IIKF LQEH GSDS FLAE HKLL GNIK NVAK TANK DHLV TAYN HLFE TKRF KGTE SISK VSEQ VKNV KLNE DKPK ETKS EETL DEGP PKYT KSVL KKGD KTNF PKKG DVVH CWYT GTLQ DGTV FDTN IQTS AKKK KNAK PLSF KVGV GKVI RGWD EALL TMSK GEKA RLEI EPEW AYGK KGQP DAKI PPNA KLTF EVEL VDID |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | FKBP-3; FKBP25; PPIase; FKBP-25; FKBP3 |
Positive Sample: | HeLa,MCF-7,BT-474 |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 25kDa |
Observed MW: | 30kDa |
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Purification Method: | Affinity purification |
Gene ID: | 2287 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |