The FITC Anti-Mouse Perforin Antibody (S16009A) is a powerful tool designed for researchers studying perforin, a key protein involved in immune response and cytotoxic activity. This antibody, optimized for use in mouse samples, is raised in a way to ensure high reactivity and specificity. It is validated for various applications such as flow cytometry and immunofluorescence, allowing for precise detection and visualization of perforin in different cell populations.Perforin is an essential component of the immune system, particularly in the function of cytotoxic lymphocytes that target and eliminate infected or abnormal cells. By targeting perforin, researchers can gain insights into the mechanisms of immune-mediated cell death and the regulation of immune responses.
This antibody provides a reliable tool for investigating perforin's role in immunity, making it ideal for studies in immunology, infectious diseases, and cancer immunotherapy.Understanding perforin's function and regulation is crucial for advancing our knowledge of immune defense mechanisms and developing novel therapeutic strategies. The FITC Anti-Mouse Perforin Antibody offers reliable performance and specificity, making it a valuable asset for researchers exploring immune responses and cytotoxic pathways in various experimental settings.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P10820
Gene ID:
18646Â
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.