FGF20 Antibody (PACO01892)
- SKU:
- PACO01892
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
FGF20 Antibody (PACO01892)
The FGF20 Polyclonal Antibody (PACO01892) is a crucial tool for researchers studying the Fibroblast Growth Factor 20 (FGF20) protein. FGF20 is a member of the FGF family known for its role in promoting cell growth, development, and differentiation. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in immunohistochemistry applications.With its ability to specifically bind to the FGF20 protein, this antibody facilitates the detection and analysis of FGF20 in a variety of cell types. Researchers in the fields of developmental biology, cell signaling, and cancer research can benefit from using this antibody to investigate the functions and mechanisms of FGF20 in cellular processes.
FGF20 has been implicated in various pathologies, including cancer and neurodegenerative disorders, making it a promising target for therapeutic interventions. By understanding the role of FGF20 in these diseases, researchers can develop novel treatment strategies that target this growth factor and its signaling pathways. The FGF20 Polyclonal Antibody is a valuable tool for advancing research in these areas and uncovering new insights into the functions of FGF20 in health and disease.
| Antibody Name: | FGF20 Antibody |
| Antibody SKU: | PACO01892 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human FGF-20. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | FGF20; Fibroblast growth factor 20; FGF-20 |
| UniProt Protein Function: | FGF20: Neurotrophic factor that regulates central nervous development and function. Belongs to the heparin-binding growth factors family. |
| UniProt Protein Details: | Protein type:Cytokine Chromosomal Location of Human Ortholog: 8p22 Cellular Component: extracellular region Molecular Function:1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity Biological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; phosphoinositide-mediated signaling; regulation of phosphoinositide 3-kinase cascade; signal transduction Disease: Renal Hypodysplasia/aplasia 2 |
| NCBI Summary: | The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q9NP95 |
| NCBI GenInfo Identifier: | 13626702 |
| NCBI Gene ID: | 26281 |
| NCBI Accession: | Q9NP95.1 |
| UniProt Secondary Accession: | Q9NP95,B2RPH5, |
| UniProt Related Accession: | Q9NP95 |
| Molecular Weight: | 23,499 Da |
| NCBI Full Name: | Fibroblast growth factor 20 |
| NCBI Synonym Full Names: | fibroblast growth factor 20 |
| NCBI Official Symbol: | FGF20Â Â |
| NCBI Official Synonym Symbols: | RHDA2; FGF-20Â Â |
| NCBI Protein Information: | fibroblast growth factor 20 |
| UniProt Protein Name: | Fibroblast growth factor 20 |
| Protein Family: | Fibroblast growth factor |
| UniProt Gene Name: | FGF20Â Â |
| UniProt Entry Name: | FGF20_HUMAN |
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