FGF16 Antibody (PACO19656)
- SKU:
- PACO19656
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
FGF16 Antibody (PACO19656)
The FGF16 Polyclonal Antibody (PAC019656) is a valuable tool for researchers studying the fibroblast growth factor 16 (FGF16) protein. This antibody, generated in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the FGF16 protein, this antibody enables precise detection and analysis in various cell types, making it ideal for investigations in the fields of developmental biology and cancer research.FGF16 is a member of the fibroblast growth factor family, known for its role in cell proliferation, differentiation, and survival.
Its involvement in various physiological processes makes it a target of interest for understanding development, tissue repair, and disease pathogenesis. The FGF16 Polyclonal Antibody offers researchers a reliable tool to explore the functions and mechanisms of FGF16, leading to potential insights into therapeutic interventions for diseases related to aberrant FGF16 signaling.
| Antibody Name: | FGF16 Antibody (PACO19656) |
| Antibody SKU: | PACO19656 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human FGF16 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19656(FGF16 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19656(FGF16 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue. |
| Synonyms: | fibroblast growth factor 16 |
| UniProt Protein Function: | FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.Protein type: CytokineChromosomal Location of Human Ortholog: Xq13Cellular Component: extracellular region; extracellular spaceMolecular Function: 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activityBiological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; metabolic process; organ morphogenesis; phosphoinositide-mediated signaling; regulation of endothelial cell proliferation; regulation of MAP kinase activity; regulation of phosphoinositide 3-kinase cascade; response to temperature stimulus; signal transductionDisease: Metacarpal 4-5 Fusion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014] |
| UniProt Code: | O43320 |
| NCBI GenInfo Identifier: | 6015145 |
| NCBI Gene ID: | 8823 |
| NCBI Accession: | O43320.1 |
| UniProt Secondary Accession: | O43320 |
| UniProt Related Accession: | O43320 |
| Molecular Weight: | 23,759 Da |
| NCBI Full Name: | Fibroblast growth factor 16 |
| NCBI Synonym Full Names: | fibroblast growth factor 16 |
| NCBI Official Symbol: | FGF16Â Â |
| NCBI Official Synonym Symbols: | MF4; FGF-16Â Â |
| NCBI Protein Information: | fibroblast growth factor 16 |
| UniProt Protein Name: | Fibroblast growth factor 16 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Fibroblast growth factor |
| UniProt Gene Name: | FGF16Â Â |
| UniProt Entry Name: | FGF16_HUMAN |
| Antibodies |
| FGF16 Antibody (PACO02117) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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