The FGF15 Antibody (PAC05274) is a valuable tool for researchers studying fibroblast growth factor 15 (FGF15), a crucial protein involved in various physiological processes, such as bile acid synthesis and metabolism. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.FGF15, also known as FGF19 in humans, is a key regulator of bile acid homeostasis and metabolism, making it a promising target for therapeutic interventions in metabolic disorders, liver diseases, and gastrointestinal conditions. By targeting FGF15 with this antibody, researchers can investigate its function, regulation, and potential as a therapeutic target in various disease contexts.
With its ability to specifically bind to FGF15 protein, this antibody enables accurate detection and analysis in different cell types and tissues, making it suitable for studies in metabolic research, liver biology, and drug development. By understanding the role of FGF15 in human health and disease, researchers can contribute valuable insights to the development of novel therapies and interventions targeting FGF15-related pathways.
Antibody Name:
Fgf15 Antibody (PACO52274)
Antibody SKU:
PACO52274
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:5000
Species Reactivity:
Mouse, Rat
Immunogen:
Recombinant Mouse Fibroblast growth factor 15 protein (26-218AA)
Western Blot. Positive WB detected in: Mouse brain tissue, Mouse stomach tissue, Mouse skeletal muscle tissue, Rat heart tissue, Rat liver tissue, Rat spleen tissue. All lanes: Fgf15 antibody at 3.5µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 26 kDa. Observed band size: 26 kDa.
Background:
Involved in the suppression of bile acid, biosynthesis through down-regulation of CYP7A1 expression.
Synonyms:
Fibroblast growth factor 15 (FGF-15), Fgf15
UniProt Protein Function:
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
