Fcmr Antibody (PACO26637)
- SKU:
- PACO26637
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Fcmr Antibody (PACO26637)
The FCMR Polyclonal Antibody (PACO26637) is a valuable tool for researchers studying the FCMR protein, a cell surface receptor involved in immune regulation and antibody production. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in various applications including Western blot and immunofluorescence.FCMR, also known as Fcα/μR, plays a crucial role in the immune system by regulating B cell function and antibody production. It is involved in the clearance of immune complexes and the modulation of immune responses, making it a key player in the body's defense against infections and diseases.
Research on FCMR has implications for autoimmune disorders, infectious diseases, and cancer immunotherapy.By using the FCMR Polyclonal Antibody, researchers can detect and study the FCMR protein in different cell types and tissues, furthering our understanding of its role in immune regulation. This antibody is a valuable tool for immunologists and cancer researchers looking to explore the mechanisms of immune response and develop novel therapeutic strategies.
| Antibody Name: | Fcmr Antibody (PACO26637) |
| Antibody SKU: | PACO26637 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse, Rat |
| Immunogen: | Recombinant Mouse Fas apoptotic inhibitory molecule 3 protein (18-262AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Fcmr antibody at 2µg/ml Lane 1: Rat spleen tissue Lane 2: Rat kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 48 kDa Observed band size: 48 kDa . |
| Background: | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, Rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
| Synonyms: | Fas apoptotic inhibitory molecule 3 (IgM Fc fragment receptor) (Regulator of Fas-induced apoptosis Toso), Fcmr, Faim3 Toso |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A1KXC4 |
| NCBI GenInfo Identifier: | 62460639 |
| NCBI Gene ID: | 69169 |
| NCBI Accession: | NP_081252.1 |
| UniProt Secondary Accession: | A1KXC4 |
| UniProt Related Accession: | A1KXC4 |
| Molecular Weight: | |
| NCBI Full Name: | fas apoptotic inhibitory molecule 3 |
| NCBI Synonym Full Names: | Fc fragment of IgM receptor |
| NCBI Official Symbol: | Fcmr  |
| NCBI Official Synonym Symbols: | Toso; Faim3; FcmuR; 1810037B05Rik  |
| NCBI Protein Information: | fas apoptotic inhibitory molecule 3 |
| UniProt Protein Name: | Fas apoptotic inhibitory molecule 3 |
| UniProt Synonym Protein Names: | Regulator of Fas-induced apoptosis Toso |
| Protein Family: | Fas apoptotic inhibitory molecule |
| UniProt Gene Name: | Faim3Â Â |
| UniProt Entry Name: | FAIM3_MOUSE |
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