The FCHO2 Polyclonal Antibody (CAB14956) is a valuable tool for research involving FCHO2, a protein involved in clathrin-mediated endocytosis, a crucial process for cellular uptake of nutrients and signaling molecules. This antibody, developed in rabbits, exhibits strong reactivity with human samples and has been validated for Western blot applications. By targeting the FCHO2 protein, this antibody allows for the detection and analysis of FCHO2 expression in various cell types, making it ideal for studies in cell biology and molecular biology.FCHO2 plays a pivotal role in the internalization of membrane proteins and the regulation of signaling pathways involved in cell growth and differentiation.
Understanding the function of FCHO2 is essential for unraveling the mechanisms underlying endocytosis and its impact on cellular processes. Research on FCHO2 may provide insights into diseases related to aberrant endocytic trafficking, such as cancer, neurodegenerative disorders, and infectious diseases. By uncovering the role of FCHO2 in cellular physiology, researchers may identify potential targets for therapeutic interventions aiming to regulate endocytosis for therapeutic benefit.
Product Name:
FCHO2 Rabbit Polyclonal Antibody
SKU:
CAB14956
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human FCHO2 (NP_620137.2).
Enables identical protein binding activity. Involved in clathrin coat assembly and clathrin-dependent endocytosis. Located in clathrin-coated pit and clathrin-coated vesicle.
Purification Method:
Affinity purification
Gene ID:
115548
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using FCHO2 Rabbit pAb (CAB14956) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
