FBXO8 Rabbit Polyclonal Antibody (CAB17681)
- SKU:
- CAB17681
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | FBXO8 Rabbit Polyclonal Antibody |
SKU: | CAB17681 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human FBXO8 (NP_036312.2). |
Sequence: | GLCK STWG HCSI YNKN PPLG FSFR KLYM QLDE GSLT FNAN PDEG VNYF MSKG ILDD SPKE IAKF IFCT RTLN WKKL RIYL DERR DVLD DLVT LHNF RNQF LPNA LREF FRHI HAPE ERGE YLET LITK FSHR FCAC NPDL M |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | FBS; DC10; FBX8; FBXO8 |
Positive Sample: | Mouse liver |
Conjugate: | Unconjugated |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Purification Method: | Affinity purification |
Gene ID: | 26269 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |