The FBXO10 Polyclonal Antibody (CAB14871) is a valuable tool for research involving FBXO10, a protein involved in the regulation of various cellular processes. Raised in rabbits, this antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the FBXO10 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an ideal choice for studies in cell biology and molecular biology.FBXO10 is known to play a critical role in the ubiquitin-proteasome system, where it targets specific proteins for degradation.
Its involvement in this pathway makes it a key player in cellular metabolism, growth, and signaling. Research into the function and regulation of FBXO10 is important for understanding its impact on various cellular processes and its potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic disorders.By utilizing the FBXO10 Polyclonal Antibody (CAB14871), researchers can further investigate the role of FBXO10 in cellular function and disease pathogenesis, ultimately leading to a deeper understanding of its potential as a therapeutic target in various medical conditions.
Product Name:
FBXO10 Rabbit Polyclonal Antibody
SKU:
CAB14871
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human FBXO10 (NP_036298.2).
Members of the F-box protein family, such as FBXO10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Purification Method:
Affinity purification
Gene ID:
26267
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from rat brain, using FBXO10 Rabbit pAb (CAB14871) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
