FABP3 Monoclonal Antibody [PAT9F10AT] (CPAB0675)
- SKU:
- CPAB0675
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1Â
- Clone:
- PAT9F10AT
- Applications:
- WB
- ELISA
Description
FABP3 Monoclonal Antibody [PAT9F10AT] (CPAB0675)
The FABP3 Antibody (CPAB0675) is a high-quality polyclonal antibody designed for research involving FABP3, also known as heart-type fatty acid-binding protein. FABP3 is a protein involved in the transport of fatty acids in cells, particularly in cardiac muscle tissue. This antibody is raised in rabbits and is highly reactive with human samples, making it a valuable tool for researchers studying cardiovascular diseases, metabolic disorders, and lipid metabolism. It is validated for use in Western blot applications, allowing for the detection and analysis of FABP3 in various cell types and tissues.
The study of FABP3 is important in understanding how cells utilize fatty acids for energy production and storage, especially in the context of heart health and disease. By targeting FABP3, researchers can gain insights into how it may be involved in conditions such as heart failure, diabetes, and obesity. This antibody provides a reliable means of detecting FABP3, enabling further exploration of its role in human health and disease.
Product Name: | FABP3 Antibody |
Product Sku: | CPAB0675 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human FABP3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FABP3 protein 1-133 amino acids purified from Ecoli. |
Clone: | PAT9F10AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | FABP3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG1Â |
Background: | Recombinant Fatty Acid Binding Protein is a newly introduced plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. But the concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), that makes FABP to be more cardiac specific than myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of myocardial infarct size. |
Synonyms: | Fatty acid-binding protein heart, H-FABP, Heart-type fatty acid-binding protein, Muscle fatty acid-binding protein, M-FABP, Mammary-derived growth inhibitor, MDGI, FABP3, FABP11, O-FABP. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |