The EVI2A Polyclonal Antibody (PAC026577) is a valuable tool for researchers studying the EVI2A protein, a cell surface molecule with implicated roles in immune regulation. This antibody, generated in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the EVI2A protein, this antibody enables detection and analysis in various cell types, making it ideal for research in immunology and cancer.EVI2A, also known as immune vesicle trafficking 2 protein A, is involved in immune response modulation and plays a crucial role in regulating immune homeostasis.
Understanding the function of EVI2A is important for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions, where immune dysregulation is a key factor. By targeting EVI2A, researchers can gain insights into potential therapeutic strategies for manipulating immune responses in various disease contexts.
Immunohistochemistry of paraffin-embedded human brain tissue using PACO26577 at dilution of 1:100.
Immunofluorescent analysis of HepG2 cells using PACO26577 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
Synonyms:
Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A), EVI2A, EVDA EVI2
UniProt Protein Function:
EVI2A: May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor. Belongs to the EVI2A family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; OncoproteinChromosomal Location of Human Ortholog: 17q11.2Cellular Component: integral to membraneMolecular Function: transmembrane receptor activityBiological Process: signal transduction
