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ERGIC3 Antibody (PACO04558)

SKU:
PACO04558
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
Frequently bought together:

Description

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ERGIC3 Antibody (PACO04558)

The ERGIC3 Polyclonal Antibody (PACO04558) is a valuable tool for research involving ERGIC3, a key protein involved in the process of protein transport and secretion within the cell. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By specifically targeting the ERGIC3 protein, this antibody enables precise detection and analysis in various cell types, making it a versatile tool for studies in cell biology and protein trafficking.ERGIC3, also known as ER-Golgi intermediate compartment protein 3, plays a crucial role in the sorting and packaging of proteins for transport between the endoplasmic reticulum (ER) and the Golgi apparatus.

Dysregulation of ERGIC3 function has been implicated in various human diseases, including neurodegenerative disorders and metabolic conditions. By elucidating the mechanisms of ERGIC3-mediated protein trafficking, researchers can gain insights into disease pathology and potentially identify novel therapeutic targets for intervention.Overall, the ERGIC3 Polyclonal Antibody (PACO04558) offers researchers a reliable tool for investigating the role of ERGIC3 in cellular processes and disease pathways. Its high specificity and sensitivity make it an essential reagent for studies aiming to uncover the molecular mechanisms underlying protein transport and secretion in health and disease.

Antibody Name:ERGIC3 Antibody
Antibody SKU:PACO04558
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000
Species Reactivity:Human, Mouse
Immunogen:synthesized peptide derived from the C-terminal region of human ERGIC-3.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:ERGIC3; C20orf47; ERV46; SDBCAG84; CGI-54; Endoplasmic reticulum-Golgi intermediate compartment protein 3; Serologically defined breast cancer antigen NY-BR-84
UniProt Protein Function:SDBCAG84: Possible role in transport between endoplasmic reticulum and Golgi. Belongs to the ERGIC family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Motility/polarity/chemotaxis; Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20pter-q12

Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; Golgi apparatus; integral to membrane; membrane

Biological Process: vesicle-mediated transport

UniProt Code:Q9Y282
NCBI GenInfo Identifier:37999823
NCBI Gene ID:51614
NCBI Accession:Q9Y282.1
UniProt Secondary Accession:Q9Y282,Q5JWS3, Q6ZWP7, Q9H276, Q9P1L3,
UniProt Related Accession:Q9Y282
Molecular Weight:43,772 Da
NCBI Full Name:Endoplasmic reticulum-Golgi intermediate compartment protein 3
NCBI Synonym Full Names:ERGIC and golgi 3
NCBI Official Symbol:ERGIC3  
NCBI Official Synonym Symbols:Erv46; CGI-54; PRO0989; C20orf47; NY-BR-84; SDBCAG84; dJ477O4.2  
NCBI Protein Information:endoplasmic reticulum-Golgi intermediate compartment protein 3
UniProt Protein Name:Endoplasmic reticulum-Golgi intermediate compartment protein 3
UniProt Synonym Protein Names:Serologically defined breast cancer antigen NY-BR-84
Protein Family:Endoplasmic reticulum-Golgi intermediate compartment protein
UniProt Gene Name:ERGIC3  
UniProt Entry Name:ERGI3_HUMAN

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