EPHX1 Monoclonal Antibody [PAT2E5AT] (CPAB0162)
- SKU:
- CPAB0162
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT2E5AT
- Applications:
- WB
- ELISA
Description
EPHX1 Monoclonal Antibody [PAT2E5AT] (CPAB0162)
The EPHX1 Polyclonal Antibody (CPAB0162) is a vital tool for researchers studying the EPHX1 enzyme, which plays a crucial role in the detoxification of xenobiotics and the metabolism of various compounds in the body. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications.EPHX1, also known as epoxide hydrolase, is involved in the metabolism of numerous chemicals and drugs, making it a key player in drug metabolism and chemical detoxification pathways. Research on EPHX1 is essential for understanding how the body processes and eliminates these substances, which has implications for drug development, toxicology studies, and environmental health research.
By targeting the EPHX1 protein, this antibody allows for the detection and analysis of EPHX1 expression in different cell types, making it a valuable tool for studies in pharmacology, toxicology, and environmental health. Researchers interested in drug metabolism, chemical detoxification, and xenobiotic metabolism will find this antibody useful in their investigations.
Product Name: | EPHX1 Antibody |
Product Sku: | CPAB0162 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human EPHX1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human EPHX1 amino acids 21-455 purified from Ecoli. |
Clone: | PAT2E5AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | EPHX1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | Epoxide hydrolase is a vital biotransformation enzyme which converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols that can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in the EPHX1 gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. |
Synonyms: | Epoxide hydrolase 1, Microsomal epoxide hydrolase, Epoxide hydratase, EPHX1, EPHX, EPOX, MEH. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |