The EPDR1 Polyclonal Antibody (PAC016259) is a valuable tool for researchers studying EPDR1, a protein involved in cellular processes and disease pathology. Raised in rabbits, this antibody is highly specific to EPDR1 in human samples and has been validated for use in various applications, including Western blotting. By binding to the EPDR1 protein, this antibody allows for accurate detection and analysis in different cell types, making it ideal for investigation in molecular biology and disease research.EPDR1, also known as Epitelial Disk Recycling Protein 1, is known to play a critical role in cellular processes such as endocytosis and vesicle trafficking.
Its involvement in these pathways suggests its potential significance in disease states such as cancer, neurodegenerative disorders, and other conditions where cellular dysfunction is implicated. By studying the functions of EPDR1, researchers can gain insights into novel therapeutic targets and diagnostic markers for various diseases.Overall, the EPDR1 Polyclonal Antibody (PAC016259) offers researchers a reliable tool for investigating the functions and implications of EPDR1 in different biological contexts, with the potential to advance our understanding of disease mechanisms and treatment strategies.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16259(EPDR1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse brain tissue, human fetal muscle tissue, Primary antibody: PACO16259(EPDR1 Antibody) at dilution 1/850, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16259(EPDR1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Synonyms:
ependymin related 1
UniProt Protein Function:
EPDR1: is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7p14.1
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]
