The ENPEP Polyclonal Antibody (CAB6905) is a valuable tool for researchers studying ENPEP, a cell surface enzyme involved in various physiological processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically binds to the ENPEP protein, enabling accurate detection and analysis in a wide range of cell types.ENPEP, also known as aminopeptidase A, plays a crucial role in the regulation of blood pressure and kidney function. Its involvement in the renin-angiotensin system makes it a potential target for research into cardiovascular diseases, hypertension, and kidney disorders.
By understanding the function of ENPEP, researchers can uncover new insights into the mechanisms underlying these conditions and develop novel therapeutic strategies.Overall, the ENPEP Polyclonal Antibody is a valuable tool for investigating the role of ENPEP in health and disease, providing researchers with the ability to explore its functions and potential implications in various medical contexts.
Product Name:
ENPEP Rabbit Polyclonal Antibody
SKU:
CAB6905
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 708-957 of human ENPEP (NP_001968.3).
The ENPEP gene encodes glutamyl aminopeptidase, a type II integral membrane protein with an extracellular zinc-binding domain. This protein can upregulate blood pressure by cleaving the N-terminal aspartate from angiotensin II, and can regulate blood vessel formation and enhance tumorigenesis in some tissues. Along with ANPEP and DPP4, ENPEP was found to be a candidate co-receptor for the coronavirus SARS-CoV-2, which causes COVID-19.
Purification Method:
Affinity purification
Gene ID:
2028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using ENPEP Rabbit pAb (CAB6905) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
