EGFR Polyclonal Antibody (CAB21740)
- SKU:
- CAB21740
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Frequently bought together:
Description
Product Name: | EGFR Polyclonal Antibody |
SKU: | CAB21740 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human EGFR (NP_005219.2). |
Sequence: | SINA TNIK HFKN CTSI SGDL HILP VAFR GDSF THTP PLDP QELD ILKT VKEI TGFL LIQA WPEN RTDL HAFE NLEI IRGR TKQH GQFS LAVV SLNI TSLG L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ERBB; ERRP; HER1; mENA; ERBB1; PIG61; NISBD2; FR |
Positive Sample: | HeLa, |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endoplasmic reticulum membrane, Endosome, Endosome membrane, Golgi apparatus membrane, Nucleus membrane, Nucleus, Secreted, Single-pass type I membrane protein. |
Calculated MW: | 134kDa |
Observed MW: | 175kDa/ |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).
Purification Method: | Affinity purification |
Gene ID: | 1956 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |