EDA Rabbit Polyclonal Antibody (CAB2905)
- SKU:
- CAB2905
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | EDA Rabbit Polyclonal Antibody |
SKU: | CAB2905 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 62-182 of human EDA (NP_001390.1). |
Sequence: | LELR SELR RERG AESR LGGS GTPG TSGT LSSL GGLD PDSP ITSH LGQP SPKQ QPLE PGEA ALHS DSQD GHQM ALLN FFFP DEKP YSEE ESRR VRRN KRSK SNEG ADGP VKNK KKGK KAGP P |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ED1; HED; EDA1; EDA2; HED1; ODT1; XHED; ECTD1; XLHED; ED1-A1; ED1-A2; EDA-A1; EDA-A2; TNLG7C; STHAGX1; EDA |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass type II membrane protein. |
Calculated MW: | 41kDa |
Observed MW: | 41kDa |
The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1896 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |