The DYNLRB2 Polyclonal Antibody (PACO05466) is a valuable tool for researchers studying DYNLRB2, a protein involved in various cellular processes, including intracellular transport and cell division. This antibody, produced in rabbits, has high specificity for human samples and is validated for use in Western blotting applications. By binding to the DYNLRB2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and molecular biology.DYNLRB2, also known as dynein light chain roadblock-type 2, is essential for proper functioning of the dynein motor complex, which is responsible for intracellular transport along microtubules.
Dysregulation of DYNLRB2 has been implicated in various diseases, including neurodegenerative disorders and certain cancers. By studying the role of DYNLRB2 in different cellular processes, researchers can gain insights into potential therapeutic targets for these conditions.This antibody provides a reliable tool for researchers interested in unraveling the functions of DYNLRB2 and its involvement in disease pathways. Its high specificity and sensitivity make it a valuable asset for studies aimed at understanding the molecular mechanisms underlying cellular processes regulated by DYNLRB2.
Antibody Name:
DYNLRB2 Antibody (PACO05466)
Antibody SKU:
PACO05466
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:10000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human Dynein LC 2B.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
DYNLRB2: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Belongs to the GAMAD family.Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 16q23.3Cellular Component: microtubule; cytoplasmic dynein complexMolecular Function: microtubule motor activityBiological Process: metabolic process; transport; organelle organization and biogenesis; microtubule-based movement
