The DUX4 Antibody (PAC052982) is a polyclonal antibody designed for research involving the DUX4 protein, which is implicated in the pathogenesis of facioscapulohumeral muscular dystrophy (FSHD). This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications including Western blot and immunofluorescence.The DUX4 protein is a transcription factor that is normally silenced in adult tissues but is aberrantly expressed in FSHD, leading to muscle degeneration. Research into the role of DUX4 in muscle pathology is crucial for understanding the molecular mechanisms underlying FSHD and for developing potential therapies for this devastating disease.
This antibody binds specifically to the DUX4 protein, enabling researchers to detect and analyze its expression in various cell types and tissues. By studying the activity and regulation of DUX4, scientists can gain insights into the disease process of FSHD and potentially identify new targets for therapeutic intervention. Additionally, this antibody may also be useful for investigations into other conditions or diseases where DUX4 expression is implicated.
Antibody Name:
DUX4 Antibody (PACO52982)
Antibody SKU:
PACO52982
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Double homeobox protein 4 protein (217-402AA)
