The DSBA Monoclonal Antibody (MACO0218) offered by Assaygenie is a valuable tool for researchers studying the DSBA protein, which is involved in cellular redox regulation. This antibody, produced using hybridoma technology, exhibits high specificity and sensitivity for detecting DSBA in various samples, particularly in Western blot applications. DSBA, a key player in maintaining cellular oxidative balance, is known for its critical role in protecting cells from oxidative stress and promoting cell survival. Dysregulation of DSBA function has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
Therefore, understanding the function and regulation of DSBA is essential for developing targeted therapies to combat these conditions.The DSBA Monoclonal Antibody (MACO0218) not only enables accurate detection and quantification of DSBA levels in different cell types but also provides insights into the mechanisms underlying redox signaling pathways. Its versatility and reliability make it an invaluable tool for researchers in the fields of biochemistry, molecular biology, and pharmacology seeking to unravel the mysteries of cellular redox regulation and its impact on human health.
Product Name:
Anti-DsbA Antibody
Product Sku:
MACO0218
Size:
100ul
Host Species:
Mouse
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:5000
Species Reactivity:
E.coli
Immunogen:
Full Length (Escherichia coli) Disulfide Oxidoreductase, isolated from E. coli.
Form:
Liquid
Storage Buffer:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Purification Method:
Antigen Affinity Purified
Clonality:
Monoclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Background:
Synonyms:
hypothetical protein
UniProt Protein Function:
Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.
UniProt Protein Details:
NCBI Summary:
DsbA has a role in cytochrome C synthesis. [More information is available at EcoGene: EG11297].
