The DRC7 Polyclonal Antibody (PAC037626) is a valuable tool for researchers studying the DRC7 protein, a key regulator of immune responses. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in Western blot applications. By binding to the DRC7 protein, this antibody enables researchers to detect and analyze DRC7 levels in a variety of cell types, making it well-suited for studies in immunology and cancer research.DRC7, also known as a crucial immune regulator, plays a significant role in modulating immune responses and maintaining immune homeostasis.
Understanding the function of DRC7 is essential for research aimed at developing new therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. By studying DRC7 activity, researchers may uncover new insights into immune regulation and potentially identify novel targets for therapeutic intervention.
Antibody Name:
DRC7 Antibody (PACO37626)
Antibody SKU:
PACO37626
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Dynein regulatory complex subunit 7 protein (1-300AA)
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37626 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO37626 at dilution of 1:100.
Background:
Key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility.
Synonyms:
Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog), DRC7, C16orf50 CCDC135
UniProt Protein Function:
CCDC135: Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility. Belongs to the CCDC135 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16q21Cellular Component: cytoplasm; cytoskeletonMolecular Function: protein binding